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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLCNKA
All Species:
17.58
Human Site:
S374
Identified Species:
35.15
UniProt:
P51800
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51800
NP_001036169.1
687
75285
S374
W
A
L
M
T
Q
N
S
S
P
P
W
P
E
E
Chimpanzee
Pan troglodytes
XP_525229
687
75266
S374
W
A
L
M
T
Q
N
S
S
P
P
W
P
E
E
Rhesus Macaque
Macaca mulatta
XP_001091784
740
81203
S374
W
G
L
M
T
R
N
S
S
P
P
W
P
E
E
Dog
Lupus familis
XP_544547
687
75469
S374
W
A
L
M
T
R
N
S
S
P
P
W
P
Q
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9WUB7
687
75650
A374
W
A
L
M
T
R
N
A
S
P
P
W
P
A
E
Rat
Rattus norvegicus
Q06393
687
75551
S374
W
A
L
M
T
R
N
S
S
P
P
W
P
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425749
696
76448
A372
W
F
V
L
A
Q
N
A
S
M
A
A
T
Q
L
Frog
Xenopus laevis
NP_001079308
689
76782
N375
W
W
I
S
L
S
Q
N
S
S
L
D
R
S
P
Zebra Danio
Brachydanio rerio
NP_956676
693
75983
I394
W
Y
S
I
S
Q
N
I
S
A
L
P
E
P
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGH7
1193
133629
V494
W
S
R
D
D
L
T
V
E
Q
A
A
V
V
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P60300
763
83497
K397
I
G
R
S
G
N
F
K
K
Y
Q
C
P
P
G
Baker's Yeast
Sacchar. cerevisiae
P37020
779
87664
F409
T
E
S
M
G
I
L
F
H
E
C
V
K
N
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.2
81.3
87.4
N.A.
82.5
83.2
N.A.
N.A.
60
61.9
43.5
N.A.
27.4
N.A.
N.A.
N.A.
Protein Similarity:
100
97.5
86.2
93
N.A.
90.8
91.2
N.A.
N.A.
73.5
78.5
62.1
N.A.
39.8
N.A.
N.A.
N.A.
P-Site Identity:
100
100
86.6
86.6
N.A.
80
86.6
N.A.
N.A.
26.6
13.3
26.6
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
100
N.A.
93.3
93.3
N.A.
N.A.
53.3
26.6
46.6
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.4
24.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.4
43.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
42
0
0
9
0
0
17
0
9
17
17
0
17
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
9
9
0
0
0
% C
% Asp:
0
0
0
9
9
0
0
0
0
0
0
9
0
0
9
% D
% Glu:
0
9
0
0
0
0
0
0
9
9
0
0
9
25
50
% E
% Phe:
0
9
0
0
0
0
9
9
0
0
0
0
0
0
0
% F
% Gly:
0
17
0
0
17
0
0
0
0
0
0
0
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
9
0
9
9
0
9
0
9
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
9
9
0
0
0
9
0
0
% K
% Leu:
0
0
50
9
9
9
9
0
0
0
17
0
0
0
9
% L
% Met:
0
0
0
59
0
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
9
67
9
0
0
0
0
0
9
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
50
50
9
59
17
9
% P
% Gln:
0
0
0
0
0
34
9
0
0
9
9
0
0
17
9
% Q
% Arg:
0
0
17
0
0
34
0
0
0
0
0
0
9
0
0
% R
% Ser:
0
9
17
17
9
9
0
42
75
9
0
0
0
9
0
% S
% Thr:
9
0
0
0
50
0
9
0
0
0
0
0
9
0
9
% T
% Val:
0
0
9
0
0
0
0
9
0
0
0
9
9
9
0
% V
% Trp:
84
9
0
0
0
0
0
0
0
0
0
50
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
0
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _